1.1.1.325: sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

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For detailed information about sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming), go to the full flat file.

Reaction

Synonyms

MDSPR, sepiapterin reductase, SPR

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

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Results	in table
93	AA Sequence
3	Cloned(Commentary)
3	Cofactor
1	Crystallization (Commentary)
1	Expression
3	General Information
1	General Stability
2	Inhibitors
1	Ki Value [mM]
5	KM Value [mM]
1	Localization
4	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
3	Organism
2	Pathway
3	pH Optimum
1	pH Range
3	Purification (Commentary)
2	Reaction
3	Reference
12	Source Tissue
7	Substrates and Products (Substrate)
3	Subunits
5	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Turnover Number [1/s]

Reaction

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Reaction on EC 1.1.1.325 - sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)

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REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

L-threo-7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+

(1)

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L-threo-tetrahydrobiopterin + 2 NADP+ = 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H+

(2)

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