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1.1.1.311: (S)-1-phenylethanol dehydrogenase

This is an abbreviated version!
For detailed information about (S)-1-phenylethanol dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.311

Reaction

(S)-1-phenylethanol
+
NAD+
=
acetophenone
+
NADH
+
H+

Synonyms

(S)-PED, PED, PedH, prelog-specific NADH-dependent (S)-1-phenylethanol dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.311 (S)-1-phenylethanol dehydrogenase

Crystallization

Crystallization on EC 1.1.1.311 - (S)-1-phenylethanol dehydrogenase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
docking simulation for prochiral ketone and beta-keto ester substrates
sitting drop method in a buffer containing 12-18% PEG 8000, 0.05 M potassium phosphate, pH 7.5 and 3% 2-methyl-2,4-pentanediol. The structure of the apo-form of the enzyme is solved with a resolution at 2.1 A. The enzyme soaked with NAD+ and the inhibitor (R)-1-phenylethanol forms a different crystal form containing two subunits in the asymmetric unit