1.1.1.31: 3-hydroxyisobutyrate dehydrogenase

This is an abbreviated version!
For detailed information about 3-hydroxyisobutyrate dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.31

1.1.1.31

semialdehyde

3-hydroxypropionate

3-hydroxyacids

methylmalonate

brasilense

tartronate

alpha-ketoacids

Reaction

Synonyms

3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxyisobutyrate dehydrogenase-I, 3-hydroxyisobutyric acid dehydrogenase, 3HIBDH-IV, 3HIBDHI, At4g20930, AtHDH1, beta-hydroxyisobutyrate dehydrogenase, HDH1, HIBADH, HIBDH

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.31 3-hydroxyisobutyrate dehydrogenase

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Results	in table
7	Activating Compound
13566	AA Sequence
2	Application
1	CAS Registry Number
11	Cloned(Commentary)
25	Cofactor
2	Crystallization (Commentary)
12	Disease/ Diagnostics
2	Expression
9	General Information
35	Inhibitors
24	kcat/KM [mM/s]
60	KM Value [mM]
4	Localization
6	Metals/Ions
18	Molecular Weight [Da]
34	Natural Substrates/ Products (Substrates)
67	Organism
5	Pathway
49	PDB ID
14	pH Optimum
9	pH Range
3	pH Stability
14	Protein Variants
18	Purification (Commentary)
1	Reaction
3	Reaction Type
45	Reference
27	Source Tissue
13	Specific Activity [micromol/min/mg]
1	Storage Stability
101	Substrates and Products (Substrate)
19	Subunits
23	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
5	Temperature Range [°C]
3	Temperature Stability [°C]
27	Turnover Number [1/s]

KM Value

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KM Value on EC 1.1.1.31 - 3-hydroxyisobutyrate dehydrogenase

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4.56

(R)-3-hydroxyisobutyrate

Mycobacterium tuberculosis

P9WNY5

at pH 8.5 and 30°C

760528

0.12 - 0.687

(S)-3-hydroxyisobutyrate

5 entries

2-methyl-D,L-serine

Pseudomonas putida

286551

0.687

3-hydroxy-2-methylpropanoate

Arabidopsis thaliana

Q9SUC0

25°C, pH 8.5

762158

0.12

3-hydroxyisobutyric acid

Homo sapiens

670284

2.5 - 3

3-hydroxypropanoic acid

Mycobacterium tuberculosis

P9WNY5

at pH 8.5 and 30°C

760528

16.8 - 18

3-hydroxypropionate

3 entries

1.055 - 2.09

3-hydroxypropionic acid

2 entries

0.1

D,L-3-hydroxyisobutyrate

Cereibacter sphaeroides

286523

1.25

D-3-hydroxyisobutyrate

Diutina rugosa

286547, 286551

0.12

DL-3-hydroxyisobutyrate

Sus scrofa

286549

0.056 - 0.37

L-3-hydroxyisobutyrate

7 entries

21.33 - 117.5

L-serine

4 entries

10.48 - 25.14

methyl (2S)-3-hydroxy-2-methylpropanoate

2 entries

10.37 - 24.18

methyl DL-serine

2 entries

0.022 - 2.4

NAD+

15 entries

0.24 - 0.96

NADP+

7 entries