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1.1.1.283: methylglyoxal reductase (NADPH)

This is an abbreviated version!
For detailed information about methylglyoxal reductase (NADPH), go to the full flat file.

Word Map on EC 1.1.1.283

Reaction

(S)-lactaldehyde
+
NADP+
=
2-oxopropanal
 +
NADPH
 +
H+

Synonyms

AKR, aldo-keto reductase, AlrA, CaGre2, CANTEDRAFT_112488, D-lactaldehyde dehydrogenase, EC 1.1.1.78, Gre2, GRE2 gene product, GRE2/YOL151W, Gre2p, GRE3, GRP2, Lbuc_0522, MeGR, Mer, methylglyoxal reductase, methylglyoxal reductase (NADPH dependent), methylglyoxal/isovaleraldehyde reductase, MG reductase, MG-specific aldolase reductase, MGR, More, NADPH-dependent methylglyoxal reductase, NADPH-linked aldolase reductase, PAS_chr3_0744, SakR1, YGL039w1, YGL039w2, YOL151W, YOL151w gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.283 methylglyoxal reductase (NADPH)

Cloned

Cloned on EC 1.1.1.283 - methylglyoxal reductase (NADPH)

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
gene CANTEDRAFT_112488
gene GRE2, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21 Star (DE3)
gene gre2, recombinant expression of His6-tagged type and mutant enzymes in Escherichia coli strain BL21(DE3)
gene Lbuc_0522, recombinant overexpression in Escherichia coli strain BL21(DE3)pLysS
-
gene PAS_chr3_0744
similar enzyme with NADPH-requirement for methylglyoxal reduction, that is inactive with NAD+, NADH and NADP+
-