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1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase

This is an abbreviated version!
For detailed information about 1-deoxy-D-xylulose-5-phosphate reductoisomerase, go to the full flat file.

Word Map on EC 1.1.1.267

Reaction

2-C-methyl-D-erythritol 4-phosphate
+
NADP+
=
1-deoxy-D-xylulose 5-phosphate
 +
NADPH
 +
H+

Synonyms

1-deoxy-D-xylulose 5-phosphate isomeroreductase, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 1-deoxy-D-xylulose-5-phosphate, 1-deoxy-D-xylulose-5-phosphate reductoisomerase, 1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose 5-phosphate reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase, 2C-methyl-D-erythritol 4-phosphate synthase, 2C-methyl-D-erythritol-4-phosphate synthase, AaDXR, CaDXR, deoxyxylulose 5-phosphate reductoisomerase, deoxyxylulosephosphate reductoisomerase, DOXP reductoisomerase, DOXP-reductoisomerase, DXP reductoisomerase, DXP-reductoisomerase, DXR, DXR1, DzDXR, EcDXR, FtIspC, IspC, MEP synthase, meps, methylerythritol phosphate synthase, MtbIspC, MtDXR, Os01g01710, OsDXR, PdDXR, PfDXR, PtDXR, Rv2870c, SaDXR, VvDxr, YpIspC

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase

Expression

Expression on EC 1.1.1.267 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
decreasing transcript levels in leafs fully expanded, low expression level in nonphotosynthetic tissues like root
-
elicitor treatments such as abscisic acid, NaCl, PEG6000, H2O2, and cold stress show that PtDXR is an elicitor-responsive gene. PtDXR does not exhibit diurnal changes. Overexpression of PtDXR in transgenic poplars improves tolerance to abiotic and biotic stresses. PtDXR expression is increased under the abiotic stress treatments. Treatment with 100 mM abscisic acid (ABA) for 12 h results in a transcript level of PtDXR approximately 20fold greater than the control level. Following treatment with 10% PEG 6000, the highest expression of PtDXR is evident on day 5, while with 4°C cold stress, expression levels are approximately 30fold above the control levels. The expression of PtDXR declines during the first 3 h and then increased, reaching the highest level at 24 h of 2 mM H2O2 treatment. For the abiotic stresses, 200 mM NaCl shows the greatest effect, with an approximately 60fold increase in PtDXR expression at 48 h
elicitors have significant effects on the expression level of DXR and contents of cardenolide and digitoxin
-
high transcript levels in the shoot, increasing transcript levels during leaf development, highest expression in young leaves prior to full
-
increase of transcript levels after treatment of trees with 1 mM methyl jasmonate, increase of transcript levels one day after mechanical wounding
methyljasmonate (MeJA) and especially H2O2 induce expression of SaDXR and lead to increased contents of sandalwood sesquiterpenoids, such as alpha-santalol and beta-santalol, in the stems of young sandalwood trees
MH018577
the enzyme is induced by methyljasmonate, synergistically increased by polyamines spermidine, spermine, and putrescine. 100 mg/l spermidine + 0.05 mM methyljasmonate lead to 4.1 and 2.4folds increase of cardenolide and digitoxin compared to the control, respectively. The lowest induction levels of cardenolide and digitoxin are obtained by 0.2 mM methyljasmonate without polyamine
-
transcript levels are induced by abscisic acid, methyl jasmonate and salicylic acid
transcript levels are not regulated by brassinolide
water stress induces expression of DXR, highest gene expression of DXR, and also highest carotinoid content, is observed at 70% of control