1.1.1.26: glyoxylate reductase

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For detailed information about glyoxylate reductase, go to the full flat file.

Reaction

Synonyms

GHPR, glycerate dehydrogenase, glycolate oxidase, glyoxylate reductase isoform 1, glyoxylate reductase/hydroxypyruvate reductase, glyoxylate/hydroxypyruvate reductase, glyoxylic acid reductase, GLYR1, GLYR2, GRHPR, GxrA, HPR1, NADH-dependent glyoxylate reductase, NADH-glyoxylate reductase, reductase, glyoxylate, SSO3187, succinic semialdehyde/glyoxylate reductase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.26 glyoxylate reductase

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Results	in table
1251	AA Sequence
2	Application
1	CAS Registry Number
6	Cloned(Commentary)
42	Cofactor
1	Crystallization (Commentary)
156	Disease/ Diagnostics
2	Expression
10	General Information
20	Inhibitors
31	KM Value [mM]
19	Localization
14	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
36	Organism
8	Pathway
12	PDB ID
11	pH Optimum
6	pH Range
8	Protein Variants
10	Purification (Commentary)
2	Reaction
2	Reaction Type
34	Reference
38	Source Tissue
22	Specific Activity [micromol/min/mg]
2	Storage Stability
67	Substrates and Products (Substrate)
12	Subunits
26	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
19	Turnover Number [1/s]

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Application on EC 1.1.1.26 - glyoxylate reductase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

diagnostics

Homo sapiens

Q9UBQ7

enzyme glyoxylate reductase/hydroxypyruvate reductase is a prognostic marker for hepatocellular carcinoma patients after curative resection. Patients with negative GRHPR both in tumor tissues and nontumoral tissues have a significantly shorter survival time than those with positive GRHPR. Multivariate analysis establishes that GRHPR is detected in nontumoral tissues as an independent prognostic factor for patients with hepatocellular carcinoma, overview

739241

medicine

Homo sapiens

-

identification of point mutations and minor deletions resulting in primary hyperoxaluria type 2

655702