1.1.1.248: salutaridine reductase (NADPH)
This is an abbreviated version!
For detailed information about salutaridine reductase (NADPH), go to the full flat file.
Reaction
Synonyms
More, PsSAR, reductase, salutaridine 7-, SalR, salutaridine 7-reductase, salutaridine reductase
ECTree
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pH Range
pH Range on EC 1.1.1.248 - salutaridine reductase (NADPH)
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4.5 - 7.5
the enzyme shows a steep decrease by 90% of activity within 1.5 pH units on both sides of the optimum at pH 6.0 for the reduction reaction
4.7 - 7.5
sharp increase in activity at pH 4.7, half-maximal activity at pH 7.5, inactive at pH 9.0, recombinant enzyme, reduction reaction
5.8 - 7.8
-
50% of maximal activity at pH 5.8 and at pH 7.8, formation of (7S)-salutaridinol
8.5 - 10
-
50% of maximal activity at pH 5.8 and at pH 7.8, formationof salutaridine
9 - 10
maximal activity at pH 9.5, sharp decline in activity at pH 10.0, oxidation reaction, recombinant enzyme