1.1.1.230: 3alpha-hydroxyglycyrrhetinate dehydrogenase

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For detailed information about 3alpha-hydroxyglycyrrhetinate dehydrogenase, go to the full flat file.

Reaction

Synonyms

dehydrogenase, 3alpha-hydroxyglycyrrhetinate

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.230 3alpha-hydroxyglycyrrhetinate dehydrogenase

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Results	in table
1	Activating Compound
1	CAS Registry Number
2	Cofactor
1	Inhibitors
4	KM Value [mM]
2	Localization
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
4	Organism
2	pH Optimum
1	Purification (Commentary)
1	Reaction
3	Reaction Type
4	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
3	Substrates and Products (Substrate)
1	Subunits
1	Synonyms
1	Systematic Name

Substrates Products

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Substrates Products on EC 1.1.1.230 - 3alpha-hydroxyglycyrrhetinate dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

3alpha-hydroxy-18alpha-glycyrrhetic acid + NADP+

3-keto-18alpha-glycyrrhetic acid + NADPH

[Clostridium] innocuum

-

-

286341

-

286341

r

3alpha-hydroxyglycyrrhetic acid + NADP+

3-ketoglycyrrhetic acid + NADPH

2 entries

3alpha-hydroxyglycyrrhetic acid + NADP+

3-ketoglycyrrhetic acid + NADPH

[Clostridium] innocuum

-

oxidation of 3alpha-hydroxy group faster than reduction of 3-keto group, not accepted as substrates: 3beta-hydroxyglycyrrhetic acid, steroids or bile acids containing 3alpha-hydroxy or 3-keto group

286341

-

286341

r

3alpha-hydroxyglycyrrhetic acid + NADP+

3-ketoglycyrrhetic acid + NADPH

[Clostridium] innocuum

-

oxidation of 3alpha-hydroxy group faster than reduction of 3-keto group

286341

-

286341

r