1.1.1.202: 1,3-propanediol dehydrogenase
This is an abbreviated version!
For detailed information about 1,3-propanediol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.202
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1.1.1.202
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pneumoniae
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klebsiella
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dehydratase
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synthesis
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fed-batch
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butyricum
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freundii
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citrobacter
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3-hydroxypropionic
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dissimilation
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1,2-propanediol
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pasteurianum
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eutropha
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biodiesel
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reuteri
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industry
- 1.1.1.202
- pneumoniae
- klebsiella
- dehydratase
- synthesis
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fed-batch
- butyricum
- freundii
- citrobacter
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3-hydroxypropionic
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dissimilation
- 1,2-propanediol
- pasteurianum
-
eutropha
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biodiesel
- reuteri
- industry
Reaction
Synonyms
(NADH)-linked 1,3-PD oxidoreductase, 1,3-PD dehydrogenase, 1,3-PD oxidoreductase, 1,3-PD-DH, 1,3-PD:NAD+ oxidoreductase, 1,3-PDDH, 1,3-Pdiol dehydrogenase, 1,3-propanediol dehydrogenase, 1,3-propanediol oxidoreductase, 1,3-propanediol-oxidoreductase, 1,3-propanediol-oxydoreductase, 1,3-propanediol:NAD oxidoreductase, 3-hydroxypropionaldehyde reductase, ADH3, dehydrogenase, 1,3-propanediol, DhaT, lr_0030, lr_1734, NADH-dependent 1,3-PD dehydrogenase, NADH-dependent 1,3-propanediol oxidoreductase, NADH-linked 1,3-propanediol oxidoreductase, PDOR, YqhD
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 1.1.1.202 - 1,3-propanediol dehydrogenase
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REACTION DIAGRAM
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
part of the conversion of glycerol to 1,3-propanediol, not the limiting step
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
3-hydroxypropionaldehyde is an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway during fermentation of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, accumulation of 3-hydroxypropanal in broth causes an irreversible cessation of the fermentation process
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
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a key enzyme in the reductive pathway of anaerobic glycerol dissimilation converting glycerol to 1,3-propanediol in the human pathogen Klebsiella pneumoniae
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
under physiological conditions, DhaT mostly catalyzes the forward reaction
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
under physiological conditions, DhaT mostly catalyzes the forward reaction
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
3-hydroxypropionaldehyde is an inhibitory intermediary metabolite in the 1,3-propanediol synthesis pathway during fermentation of raw material required for the synthesis of polytrimethylene terephthalate and other polyester fibers, accumulation of 3-hydroxypropanal in broth causes an irreversible cessation of the fermentation process
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
reduction of the aldehyde is the preferred reaction
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r
3-hydroxypropanal + NADH + H+
propane-1,3-diol + NAD+
reduction of the aldehyde is the preferred reaction
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r
3-hydroxypropionaldehyde + NADH + H+
propane-1,3-diol + NAD+
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the enzyme is important in vivo for convertion of glycerol into propane-1,3-diol as second step after dehydration of glycerol by coenzyme B12-dependent glycerol dehydratase
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r
propane-1,3-diol + NAD+
3-hydroxypropanal + NADH
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key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol
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propane-1,3-diol + NAD+
3-hydroxypropanal + NADH
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key enzyme of the 1,3-propanediol production pathway, high enzyme synthesis and activity in the anaerobic growth phase with increased use of glycerol
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?
propane-1,3-diol + NAD+
3-hydroxypropanal + NADH
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propane-1,3-diol + NAD+
3-hydroxypropanal + NADH + H+
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r
propane-1,3-diol + NAD+
3-hydroxypropanal + NADH + H+
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r
propane-1,3-diol + NAD+
3-hydroxypropanal + NADH + H+
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r
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the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction
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?
additional information
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the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction
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?
additional information
?
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the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction
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