1.1.1.169: 2-dehydropantoate 2-reductase

This is an abbreviated version!
For detailed information about 2-dehydropantoate 2-reductase, go to the full flat file.

Word Map on EC 1.1.1.169

1.1.1.169

pantothenate

nadph-dependent

pane

hydroxymethyltransferase

ketopantoyl

2'-phosphate

fragment-based

d-2-hydroxyacid

parapsilosis

kodakarensis

Reaction

Synonyms

2-dehydropantoate 2-reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, 2-oxopantoate reductase, conjugated polyketone reductase, CPR, ilvC, ketopantoate reductase, ketopantoic acid reductase, KPA reductase, KPR, More, PanE, panG, Tk-KPR, TK1968, TK1968 protein

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.169 2-dehydropantoate 2-reductase

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Results	in table
5	Activating Compound
38923	AA Sequence
1	CAS Registry Number
16	Cloned(Commentary)
51	Cofactor
9	Crystallization (Commentary)
15	General Information
24	Inhibitors
6	kcat/KM [mM/s]
8	Ki Value [mM]
52	KM Value [mM]
5	Metals/Ions
18	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
63	Organism
7	Pathway
55	PDB ID
14	pH Optimum
2	pH Range
2	pH Stability
1	Posttranslational Modification
36	Protein Variants
15	Purification (Commentary)
4	Reaction
3	Reaction Type
46	Reference
16	Specific Activity [micromol/min/mg]
1	Storage Stability
85	Substrates and Products (Substrate)
20	Subunits
59	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
2	Temperature Range [°C]
4	Temperature Stability [°C]
14	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 1.1.1.169 - 2-dehydropantoate 2-reductase

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115000

Stenotrophomonas maltophilia

+/-5000, gel filtration

286103

140000 - 160000

Stenotrophomonas maltophilia

+/-5000, HPLC gel filtration

286103

30500

Stenotrophomonas maltophilia

3-5 * 30500 or 30000, SDS-PAGE

31100

33000

33800

calculated from 912 bp coding region

286106

33866

Escherichia coli

1 * 33000 gel filtration, 1 * 33866 elelectrospray mass spectrometry analysis, 1 * 33870 amino acid sequence

286108

33870

Escherichia coli

1 * 33000 gel filtration, 1 * 33866 elelectrospray mass spectrometry analysis, 1 * 33870 amino acid sequence

286108

34000

4 entries

34048

Thermococcus kodakarensis

Q5JGC2

2 * 34048, sequence calculation, 2 x 30000, about, recombinant enzyme, SDS-PAGE

736827

60000

Thermococcus kodakarensis

Q5JGC2

recombinant enzyme, gel filtration

736827

87000

Stenotrophomonas maltophilia

+/-5000, sedimentation equilibrium method

286103