1.1.1.169: 2-dehydropantoate 2-reductase
This is an abbreviated version!
For detailed information about 2-dehydropantoate 2-reductase, go to the full flat file.
Word Map on EC 1.1.1.169
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1.1.1.169
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pantothenate
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nadph-dependent
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pane
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hydroxymethyltransferase
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ketopantoyl
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2'-phosphate
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fragment-based
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d-2-hydroxyacid
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parapsilosis
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kodakarensis
- 1.1.1.169
- pantothenate
-
nadph-dependent
-
pane
- hydroxymethyltransferase
-
ketopantoyl
- 2'-phosphate
-
fragment-based
- d-2-hydroxyacid
-
parapsilosis
- kodakarensis
Reaction
Synonyms
2-dehydropantoate 2-reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, 2-oxopantoate reductase, conjugated polyketone reductase, CPR, ilvC, ketopantoate reductase, ketopantoic acid reductase, KPA reductase, KPR, More, PanE, panG, Tk-KPR, TK1968, TK1968 protein
ECTree
1.1.1.169 2-dehydropantoate 2-reductaseAdvanced search results
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results (Inhibitors
Inhibitors on EC 1.1.1.169 - 2-dehydropantoate 2-reductase
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INHIBITOR 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
D-pantoic acid
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noncompetitive with ketopantoic acid at saturation level of NADPH, noncompetitive with NADPH at unsaturation level of ketopantoic acid
p-chloromercuribenzoate
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sulfhydryl reagents, slightly inhibitory
CoA
strong inhibition, competitive versus NADH, effect on enzyme kinetics, overview
CoA
feedback inhibition, competitive with NADPH, the binding sites of CoA and NADP+ overlap, explaining the competitive manner of inhibition by CoA, binding structure analysis, overview
NADP+
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competitive with NADPH at unsaturation level of ketopantoic acid
additional information
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protein-ligand interaction determination and analysis
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