1.1.1.156: glycerol 2-dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about glycerol 2-dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

DHA oxidoreductase, DHAR, dihydroxy (reduced nicotinamide adenine dinucleotide phosphate) reductase, dihydroxyacetone reductase, dihydroxyacetone reductase (NADPH), GDH4, GLD2, glycerol-2-DH, glycerol:NADP 2-oxidoreductase, dihydroxyacetone forming, NADP-dependent GLDH, NADP-glycerol-2-dehydrogenase, NADPH-DHAR

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.156 glycerol 2-dehydrogenase (NADP+)

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Results	in table
16	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
11	Cofactor
1	Expression
1	General Information
8	Inhibitors
17	KM Value [mM]
2	Localization
1	Metals/Ions
7	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
16	Organism
2	Pathway
9	pH Optimum
4	Purification (Commentary)
1	Reaction
3	Reaction Type
13	Reference
18	Source Tissue
7	Specific Activity [micromol/min/mg]
35	Substrates and Products (Substrate)
2	Subunits
20	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 1.1.1.156 - glycerol 2-dehydrogenase (NADP+)

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

2-mercaptoethanol

Schizosaccharomyces pombe

-

80% inhibition at 1 mM

286040

8-hydroxyquinoline

Schizosaccharomyces pombe

-

complete inhibition at 10 mM

286040

dithiothreitol

Schizosaccharomyces pombe

-

25% inhibition at 10 mM

286040

KCl

Phycomyces blakesleeanus

-

inhibition above 100 mM

286045

L-cysteine

Schizosaccharomyces pombe

-

40% inhibition at 10 mM

286040

Mg2+

Phycomyces blakesleeanus

-

40% inhibition at 5 mM

286045

Mn2+

Phycomyces blakesleeanus

-

25% inhibition at 5 mM

286045

p-chloromercuribenzoate

Schizosaccharomyces pombe

-

strong inhibition

286040