1.1.1.149: 20alpha-hydroxysteroid dehydrogenase

This is an abbreviated version!
For detailed information about 20alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.149

1.1.1.149

progesterone

androgen

prostate

reductases

testosterone

prostaglandin

akr1cs

steroidogenic

luteal

castration-resistant

srd5a1

androstenedione

5alpha-reductase

cyp17a1

dihydrotestosterone

progestin

akr1b10

17beta-hydroxysteroid

3alpha-hsds

abiraterone

neurosteroids

luteolysis

hsd3b1

5alpha-dihydrotestosterone

17beta-hsds

enzalutamide

flufenamic

17beta

ketosteroid

allopregnanolone

3beta-hsd

17alpha

17alpha-hydroxyprogesterone

hydrogenans

pgf2alpha

hsd17b3

pre-receptor

intracrine

3-ketosteroids

dihydrodiol

scarb1

analysis

biotechnology

food industry

medicine

environmental protection

Reaction

17alpha,20alpha-dihydroxypregn-4-en-3-one

+

NAD(P)+

=

17alpha-hydroxyprogesterone

+

NAD(P)H

+

H+

Synonyms

20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 20alpha-HSD, 20alpha-HSDH, 20alpha-hydroxy steroid dehydrogenase, 20alpha-hydroxysteroid dehydrogenase, 20alpha-hydroxysteroid oxidoreductase, 20alpha-OH-SDH, 20beta-HSDH, 20beta-hydroxysteroid dehydrogenase, 3alpha-HSOR, 3alpha-hydroxysteroid oxidoreductase, AKR1C1, AKR1C14, AKR1C23, AKR1C3, AKR1C5, AKR1C9, aldo-keto reductase family 1 member C1, HSD1, More

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.149 20alpha-hydroxysteroid dehydrogenase

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
5	Activating Compound
101	AA Sequence
10	Application
1	CAS Registry Number
17	Cloned(Commentary)
89	Cofactor
17	Crystallization (Commentary)
1267	Disease/ Diagnostics
8	Expression
16	General Information
6	General Stability
16	IC50 Value
188	Inhibitors
71	kcat/KM [mM/s]
66	Ki Value [mM]
259	KM Value [mM]
6	Localization
4	Metals/Ions
34	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
129	Organism
2	Pathway
11	PDB ID
21	pH Optimum
5	pH Range
3	pH Stability
4	Posttranslational Modification
34	Protein Variants
27	Purification (Commentary)
11	Reaction
3	Reaction Type
73	Reference
1	Renatured (Commentary)
153	Source Tissue
33	Specific Activity [micromol/min/mg]
14	Storage Stability
307	Substrates and Products (Substrate)
20	Subunits
71	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
1	Temperature Range [°C]
16	Temperature Stability [°C]
77	Turnover Number [1/s]

IC50 Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

IC50 Value on EC 1.1.1.149 - 20alpha-hydroxysteroid dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

back to the top

Go to IC50 Value Search

0.0729

1-phenylcyclopentanecarboxylic acid

Homo sapiens

pH 6.5, temperature not specified in the publication

0.035

2-(4-chlorobenzylidene)cyclopentanone

Homo sapiens

pH 6.5, temperature not specified in the publication

0.0621

2-(4-chlorobenzylidene)cyclopentyl ethyl ether

Homo sapiens

pH 6.5, temperature not specified in the publication

0.003

3',3'',5',5''-tetrabromophenolphthalein

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.0986

3-phenylcyclopentanecarboxylic acid

Homo sapiens

pH 6.5, temperature not specified in the publication

0.00012

benzbromarone

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.026

Flufenamic acid

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.00041

galangin

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.0064

Hexestrol

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.00011

kaempferol

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.01

Mefenamic acid

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.00064

myricetin

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.00037

naringenin

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.000022

Phenolphthalein

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.000059

quercetin

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

0.011

Sulfobromophthalein

Oryctolagus cuniculus

-

at pH 7.4 and 37°C

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)